{"id":5624,"date":"2026-09-29T22:43:40","date_gmt":"2026-09-29T22:43:40","guid":{"rendered":"https:\/\/netguide.io\/news\/2026\/09\/29\/semaglutide-estende-la-vita-e-rallenta-linvecchiamento-nei-topi-vecchi\/"},"modified":"2026-09-29T22:43:40","modified_gmt":"2026-09-29T22:43:40","slug":"semaglutide-estende-la-vita-e-rallenta-linvecchiamento-nei-topi-vecchi","status":"publish","type":"post","link":"https:\/\/netguide.io\/news\/it\/2026\/09\/29\/semaglutide-estende-la-vita-e-rallenta-linvecchiamento-nei-topi-vecchi\/","title":{"rendered":"Semaglutide estende la vita e rallenta l&#8217;invecchiamento nei topi vecchi"},"content":{"rendered":"<div id=\"netgu-1465149939\" class=\"netgu-before-content netgu-entity-placement\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6258556257245998\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display:block;\" data-ad-client=\"ca-pub-6258556257245998\" \ndata-ad-slot=\"3494115342\" \ndata-ad-format=\"auto\"><\/ins>\n<script> \n(adsbygoogle = window.adsbygoogle || []).push({}); \n<\/script>\n<\/div><p class=\"wp-block-paragraph\"><strong>Semaglutide \u2013 il composto dietro iniezioni di perdita di peso come Ozempic e Wegovy \u2013 prolungata durata di vita e rallentato processo di invecchiamento del nucleo nei topi anziani. Un team guidato da Danica Chen all&#8217;Universit\u00e0 della California, Berkeley, insieme all&#8217;US National Institute on Aging (NIA), ha riferito i risultati del 2 settembre 2026 nella rivista <em>Natura<\/em>.<\/strong><\/p>\n<h3 class=\"wp-block-heading\">Cosa ha trovato lo studio<\/h3>\n<p class=\"wp-block-paragraph\">I ricercatori hanno trattato i topi femminili di 20 mesi \u2013 approssimativamente equivalenti all&#8217;et\u00e0 adulta avanzata negli esseri umani \u2013 con semaglutide per tre mesi. Anche dopo quella breve finestra gli animali erano pi\u00f9 vivi e pi\u00f9 curiosi dei loro coetanei, con un migliore controllo dell&#8217;zucchero e una maggiore resistenza. Un gruppo separato trattato fino alla fine della vita ha raggiunto una durata mediana di quasi 100 giorni pi\u00f9 lunga di controlli non trattati.<\/p><div id=\"netgu-570816419\" class=\"netgu-content netgu-entity-placement\"><aside class=\"deals-top deals-top--compact\">\n\n\t\t\t<h3 class=\"deals-top__title\">Top-Deals<\/h3>\n\t\n\t\t\t<ul class=\"deals-top__list\">\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/moon-knight-digital-watch-face-fuer-wear-os-4\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/deal-27-150x150.png\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">MOON KNIGHT Digital Watch Face f\u00fcr Wear OS 4+<\/span>\n\n\t\t\t\t\t\t\t<span 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class=\"deals-top__name\">Train Sim World 7: Starter Pack kostenlos f\u00fcr PS4, PS5, Xbox, PC<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t55\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/ml2u-watchfaces-fuer-wearos-im-google-play-store-2\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/2844734_1-150x150.webp\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">ML2U Watchfaces 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\/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">Kostenloses DLC-Bundle f\u00fcr Gears of War E-Day \u2013 Liquid Death Bundle<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t54\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/kostenlose-emote-im-clash-royale-store\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/share-image-clashroyale-150x150.jpg\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">Kostenlose Emote im Clash Royale-Store<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t54\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\n\t\t\t\t\t<p class=\"deals-top__more\">\n\t\t\t\t<a href=\"https:\/\/netguide.io\/deals\/\">Alle Deals ansehen \u2192<\/a>\n\t\t\t<\/p>\n\t\t\t<\/aside>\n<\/div>\n<h3 class=\"wp-block-heading\">Pi\u00f9 di perdita di peso<\/h3>\n<p class=\"wp-block-paragraph\">L&#8217;analisi dell&#8217;espressione genetica ha dimostrato che diversi segni classici dell&#8217;invecchiamento sono stati attenuati. In alcune aree l&#8217;effetto anche superato quello di restrizione calorica con il 24 per cento meno cibo. Miglioramenti inclusi:<\/p>\n<ul class=\"wp-block-list\"><li>marcatori di infiammazione pi\u00f9 bassi nel tessuto<\/li><li>migliore capacit\u00e0 rigenerativa delle cellule staminali nel midollo osseo e nel cervello<\/li><li>migliorata funzione muscolare e memoria<\/li><\/ul>\n<h3 class=\"wp-block-heading\">Nessuna prova per gli esseri umani ancora<\/h3>\n<p class=\"wp-block-paragraph\">I dati provengono esclusivamente da un modello animale; se l&#8217;effetto permanente porta a persone deve ancora essere confermato nelle sperimentazioni cliniche. Il ricercatore NIA Rafael de Cabo nota che molte malattie croniche sono profondamente radicate nel processo di invecchiamento \u2013 se un farmaco GLP-1 lo rallenta veramente, sarebbe prevista una vasta gamma di benefici clinici.<\/p>\n<p class=\"wp-block-paragraph\"><em>Fonti:<\/em> <a href=\"https:\/\/www.nature.com\/articles\/s41586-026-10940-7\" rel=\"noopener\" target=\"_blank\">Natura (Chen et al., 2026)<\/a> \u00b7 <a href=\"https:\/\/www.nih.gov\/news-events\/news-releases\/glp-1-treatment-late-life-extends-lifespan-animal-model\" rel=\"noopener\" target=\"_blank\">NIH\/NIA<\/a> \u00b7 <a href=\"https:\/\/cen.acs.org\/biological-chemistry\/semaglutide-mouse-longevity\/104\/web\/2026\/09\" rel=\"noopener\" target=\"_blank\">C&#038;EN<\/a><\/p><div id=\"netgu-588739327\" class=\"netgu-after-content netgu-entity-placement\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6258556257245998\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display:block;\" data-ad-client=\"ca-pub-6258556257245998\" \ndata-ad-slot=\"4559785002\" \ndata-ad-format=\"auto\"><\/ins>\n<script> \n(adsbygoogle = window.adsbygoogle || []).push({}); \n<\/script>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Il diabete e la perdita di peso farmaco semaglutide prolungata durata di vita di quasi 100 giorni in topi femminili vecchi e rallentato diversi segnali di invecchiamento, un nuovo studio Natura da Berkeley rapporti.<\/p>\n","protected":false},"author":1,"featured_media":2222,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[],"tags":[],"class_list":["post-5624","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"brizy_media":[],"_links":{"self":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/5624","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/comments?post=5624"}],"version-history":[{"count":1,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/5624\/revisions"}],"predecessor-version":[{"id":5625,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/5624\/revisions\/5625"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/media\/2222"}],"wp:attachment":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/media?parent=5624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/categories?post=5624"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/tags?post=5624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}