{"id":4224,"date":"2026-09-29T19:01:36","date_gmt":"2026-09-29T19:01:36","guid":{"rendered":"https:\/\/netguide.io\/news\/2026\/09\/29\/regreso-de-los-dientes-de-cultivo-japones-despeja-la-fase-1\/"},"modified":"2026-09-29T19:01:36","modified_gmt":"2026-09-29T19:01:36","slug":"regreso-de-los-dientes-de-cultivo-japones-despeja-la-fase-1","status":"publish","type":"post","link":"https:\/\/netguide.io\/news\/es\/2026\/09\/29\/regreso-de-los-dientes-de-cultivo-japones-despeja-la-fase-1\/","title":{"rendered":"Regreso de los dientes de cultivo: Japon\u00e9s despeja la fase 1"},"content":{"rendered":"<div id=\"netgu-2887105566\" class=\"netgu-before-content netgu-entity-placement\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6258556257245998\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display:block;\" data-ad-client=\"ca-pub-6258556257245998\" \ndata-ad-slot=\"3494115342\" \ndata-ad-format=\"auto\"><\/ins>\n<script> \n(adsbygoogle = window.adsbygoogle || []).push({}); \n<\/script>\n<\/div>\n<p class=\"wp-block-paragraph\"><strong>Un equipo de investigaci\u00f3n japon\u00e9s est\u00e1 probando un medicamento destinado a crecer dientes completamente nuevos. La primera fase cl\u00ednica en humanos se considera completa \u2013 sin efectos secundarios graves.<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">C\u00f3mo funciona<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">El agente activo es un anticuerpo que bloquea la prote\u00edna USAG-1. Esto aumenta las llamadas v\u00edas de se\u00f1alizaci\u00f3n BMP y provoca brotes de dientes que ya est\u00e1n presentes en la mand\u00edbula \u2013 pero normalmente &#8220;mantenimiento&#8221; \u2013 para crecer. Un equipo de la Universidad de Kyoto demostr\u00f3 originalmente el efecto en ratones y hurones; el estudio fundamental apareci\u00f3 en <em>Avances cient\u00edficos<\/em>.<\/p><div id=\"netgu-2435836322\" class=\"netgu-content netgu-entity-placement\"><aside class=\"deals-top deals-top--compact\">\n\n\t\t\t<h3 class=\"deals-top__title\">Top-Deals<\/h3>\n\t\n\t\t\t<ul class=\"deals-top__list\">\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/moon-knight-digital-watch-face-fuer-wear-os-4\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/deal-27-150x150.png\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">MOON KNIGHT Digital Watch Face f\u00fcr Wear OS 4+<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<s>0.89 \u20ac<\/s>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-discount\">-100%<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t55\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/train-sim-world-7-starter-pack-kostenlos-fuer-ps4-ps5-xbox-pc\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/capsule_616x353-11-150x150.jpg\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">Train Sim World 7: Starter Pack kostenlos f\u00fcr PS4, PS5, Xbox, PC<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t55\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/ml2u-watchfaces-fuer-wearos-im-google-play-store-2\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/2844734_1-150x150.webp\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">ML2U Watchfaces f\u00fcr WearOS im Google Play Store<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<s>1.39 \u20ac<\/s>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-discount\">-100%<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t54\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/kostenloses-dlc-bundle-fuer-gears-of-war-e-day-liquid-death-bundle\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/2844571_1-150x150.webp\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">Kostenloses DLC-Bundle f\u00fcr Gears of War E-Day \u2013 Liquid Death Bundle<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t54\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"deals-top__item\">\n\t\t\t\t\t<a class=\"deals-top__link\" href=\"https:\/\/netguide.io\/deals\/de\/deals\/kostenlose-emote-im-clash-royale-store\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img class=\"deals-top__image\" src=\"https:\/\/netguide.io\/news\/wp-content\/uploads\/sites\/15\/2026\/09\/share-image-clashroyale-150x150.jpg\" alt=\"\" width=\"52\" height=\"52\" loading=\"lazy\" \/>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<span class=\"deals-top__body\">\n\t\t\t\t\t\t\t<span class=\"deals-top__name\">Kostenlose Emote im Clash Royale-Store<\/span>\n\n\t\t\t\t\t\t\t<span class=\"deals-top__meta\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"deals-top__price\">Gratis<\/span>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<span class=\"deals-top__temperature\">\n\t\t\t\t\t\t\t54\u00b0\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\n\t\t\t\t\t<p class=\"deals-top__more\">\n\t\t\t\t<a href=\"https:\/\/netguide.io\/deals\/\">Alle Deals ansehen \u2192<\/a>\n\t\t\t<\/p>\n\t\t\t<\/aside>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Donde estan las cosas<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">La empresa Toregem Biopharma lanz\u00f3 el estudio Fase I en el Hospital Universitario de Kyoto en octubre de 2024: 30 hombres sanos de 30 a 64 a\u00f1os con al menos un molar desaparecido, principalmente para evaluar la seguridad. Esa fase es completa y se ha confirmado la seguridad. En mayo de 2026, Toregem cri\u00f3 5,3 millones de d\u00f3lares para la fase II posterior.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Todav\u00eda hay un largo camino a la aprobaci\u00f3n. Si tiene \u00e9xito, ser\u00eda la primera alternativa genuina a los implantes y puentes \u2013 dientes el cuerpo crece por s\u00ed solo.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Fuentes: <a href=\"https:\/\/dentistry.co.uk\/2026\/08\/18\/tooth-regrowth-in-adults-what-we-know-so-far\/\" rel=\"noopener\" target=\"_blank\">Dentistry.co.uk<\/a>, <a href=\"https:\/\/trial.medpath.com\/news\/japanese-researchers-begin-human-trials-for-revolutionary-tooth-regeneration-drug\" rel=\"noopener\" target=\"_blank\">Medpath<\/a>.<\/em><\/p>\n<div id=\"netgu-3809603529\" class=\"netgu-after-content netgu-entity-placement\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6258556257245998\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display:block;\" data-ad-client=\"ca-pub-6258556257245998\" \ndata-ad-slot=\"4559785002\" \ndata-ad-format=\"auto\"><\/ins>\n<script> \n(adsbygoogle = window.adsbygoogle || []).push({}); \n<\/script>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Un equipo japon\u00e9s est\u00e1 probando una droga destinada a crecer nuevos dientes. La primera fase cl\u00ednica en humanos est\u00e1 completa, sin efectos secundarios graves reportados.<\/p>\n","protected":false},"author":1,"featured_media":1690,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[],"tags":[],"class_list":["post-4224","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"brizy_media":[],"_links":{"self":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/4224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/comments?post=4224"}],"version-history":[{"count":1,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/4224\/revisions"}],"predecessor-version":[{"id":4225,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/posts\/4224\/revisions\/4225"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/media\/1690"}],"wp:attachment":[{"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/media?parent=4224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/categories?post=4224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/netguide.io\/news\/wp-json\/wp\/v2\/tags?post=4224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}